s/n4085365

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has gloss(noun) an antiviral drug that inhibits the action of reverse transcriptase in retroviruses such as HIV
reverse transcriptase inhibitor
has glosseng: Reverse transcriptase inhibitors (RTIs) are a class of antiretroviral drug used to treat HIV infection, tumors , and cancer . RTIs inhibit activity of reverse transcriptase, a viral DNA polymerase enzyme that retroviruses need to reproduce.
lexicalizationeng: reverse transcriptase inhibitor
subclass of(noun) any drug that destroys viruses
antiviral drug, antiviral agent, antiviral
has subclass(noun) an antiviral drug used against HIV; binds directly to reverse transcriptase and prevents RNA conversion to DNA; often used in combination with other drugs
non-nucleoside reverse transcriptase inhibitor, NNRTI
has subclass(noun) an antiviral drug used against HIV; is incorporated into the DNA of the virus and stops the building process; results in incomplete DNA that cannot create a new virus; often used in combination with other drugs
NRTI, nucleoside reverse transcriptase inhibitor
Meaning
German
has glossdeu: Nukleosidische Reverse-Transkriptase-Inhibitoren (engl. Nucleoside Reverse Transcriptase Inhibitors, NRTI) sind Arzneistoffe aus der Gruppe der Virostatika. Es handelt sich um Nukleosid-Analoga, die den natürlichen Nukleosiden ähneln. Ihr Ansatzpunkt ist das Enzym Reverse Transkriptase von Retroviren, die das virale RNA-Genom in DNA umschreibt. Sie konkurrieren mit natürlichen Nukleosiden, unterscheiden sich allerdings durch geringe Modifikationen an der Ribose (Zuckermolekül), d.h. sie besitzen keine 3'-Hydroxylgruppe, an der die Kettenverlängerung stattfindet.
lexicalizationdeu: Nukleosidische Reverse-Transkriptase-Inhibitoren
Indonesian
has glossind: Reverse Transcriptase Inhibitors adalah kelas obat antiretroviral yang digunakan untuk menangani infeksi HIV. Reverse Transcriptase Inhibitors merupakan sintesis DNA dari HIV.
lexicalizationind: Inhibitor transkriptase balik
Chinese
has glosszho: 核苷类逆转录酶抑制剂(Nucleoside Reverse Transcriptase Inhibitors,NRTIs),是合成HIV的DNA逆转录酶底物脱氧核苷酸的类似物,在体内转化成活性的三磷酸核苷衍生物,与天然的三磷酸脱氧核苷竞争性与HIV逆转录酶(RT)结合,抑制RT的作用,阻碍前病毒的合成。
lexicalizationzho: 核苷类逆转录酶抑制剂
Links
similare/Reverse transcriptase inhibitor
Media
media:imgReverse Transcriptase.PNG

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